Isozaki died Wednesday at his home on Japan's southern island Okinawa, according to the Bijutsu Techo, one of the country's most respected art magazines, and other media.
Isozaki won the Pritzker Architecture Prize, internationally the highest honor in the field, in 2019.
Isozaki began his architectural career under the apprenticeship of Japanese legend Kenzo Tange, a 1987 Pritzker laureate, after studying architecture at the University of Tokyo, Japan's top school.
He was one of the forerunners of Japanese architects who designed buildings overseas, transcending national and cultural boundaries, and also as a critic of urban development and city designs.
Among Isozaki's best-known works are the Museum of Contemporary Art in Los Angeles and the Palau Sant Jordi stadium in Barcelona built for the 1992 Summer Games. He also designed iconic building such as the Team Disney Building and the headquarters of the Walt Disney Company in Florida.
Born in 1931 in Oita, he was 14 when he saw the aftermath of the U.S. atomic bombings of Hiroshima and Nagaski in August 1945, which killed 210,000 people.
That led to his theory that buildings are transitory but also should please the senses.
